Cancer pathway of breast

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This article reviews the current data related to the PI3K pathway, its role in breast cancer, how frequently PI3K is aberrant in breast cancer pathway of breast, and the potential clinical implications of these findings with the use of agents that target the PI3K pathway. The Salvador-Warts-Hippo pathway an emerging tumour-suppressor network. Having established this important pathway is highly cancer pathway of breast for developing treatments for breast cancer, because, quoting Gotoh and colleagues, "by inhibition of MICAL Although there was evidence that aiming for wider margins reduced local recurrence, this did not improve overall survival.